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硬纤维瘤。后续妊娠时复发或出现新疾病的风险:一例病例报告。

Desmoid tumour. The risk of recurrent or new disease with subsequent pregnancy: a case report.

作者信息

Way J C, Culham B A

机构信息

Department of Surgery, Calgary District Hospital Group, Calgary, Alta.

出版信息

Can J Surg. 1999 Feb;42(1):51-4.

Abstract

Desmoid tumours are rare, benign tumours arising from fibrous tissue in muscle fascia or aponeurosis. They are most common in women of child-bearing age and most often appear during or after pregnancy in this age group. The recommended treatment is wide surgical excision, if possible, but unresectable tumours may be treated with radiotherapy, anticancer drugs, nonsteroidal anti-inflammatory agents or antiestrogenic compounds. The recurrence rate is high and seems to be related to the achievement of resection margins free of tumour. The literature is not specific about how to counsel women who have had a desmoid tumour and subsequently wish to have a child. Patients should be advised that these tumours may be estrogen sensitive but subsequent pregnancy is not necessarily a risk factor for recurrence or development of new disease.

摘要

硬纤维瘤是一种罕见的良性肿瘤,起源于肌筋膜或腱膜的纤维组织。它们在育龄妇女中最为常见,并且在该年龄组的孕期或产后最为常出现。推荐的治疗方法是尽可能进行广泛的手术切除,但无法切除的肿瘤可以用放射治疗、抗癌药物、非甾体抗炎药或抗雌激素化合物治疗。复发率很高,似乎与获得无肿瘤的切缘有关。关于如何为患有硬纤维瘤且随后希望生育的女性提供咨询,文献中没有具体说明。应告知患者这些肿瘤可能对雌激素敏感,但随后的怀孕不一定是复发或新疾病发生的危险因素。

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引用本文的文献

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A Rapidly Growing Abdominal Mass: Desmoid Tumor in Pregnancy.快速生长的腹部肿块:妊娠期硬纤维瘤
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Desmoid tumors in pregnant and postpartum women.妊娠和产后女性的硬纤维瘤。
Cancers (Basel). 2012 Feb 21;4(1):184-92. doi: 10.3390/cancers4010184.

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