Rubin J, Rockey D C
Division of Gastroenterology, Duke University Medical Center, Durham, NC 27710, USA.
South Med J. 1999 Feb;92(2):248-50. doi: 10.1097/00007611-199902000-00019.
We describe two postmenopausal women with ascites and elevated CA-125 level, a serologic marker used to detect ovarian cancer. Both patients had unrecognized liver disease but underwent surgical exploration for suspected ovarian disease, which subsequently revealed benign pelvic organs. Elevated serum CA-125 levels have been reported in many patients with ascites due to liver disease and cirrhosis. Thus, the presence of both ascites and an elevated CA-125 level mandates a thorough elevation for liver disease as well as for a possibility of ovarian carcinoma. These cases outline the common finding and provide insight into the management of patients with ascites and elevated CA-125 values.
我们描述了两名绝经后女性，她们患有腹水且CA-125水平升高，CA-125是一种用于检测卵巢癌的血清学标志物。两名患者均患有未被识别的肝脏疾病，但因疑似卵巢疾病接受了手术探查，结果发现盆腔器官为良性。已有报道称，许多因肝脏疾病和肝硬化导致腹水的患者血清CA-125水平会升高。因此，腹水和CA-125水平升高的情况需要对肝脏疾病以及卵巢癌的可能性进行全面评估。这些病例概述了常见的发现，并为腹水和CA-125值升高患者的管理提供了见解。
