Schepis C, Siragusa M, Palazzo R, Cavallari V
Unit of Dermatology, Oasi Institute for Research on Mental Retardation and Brain Aging (IRCCS), Troina, Italy.
Cutis. 1999 Feb;63(2):99-102.
Prurigo pigmentosa is a papular pruriginous eruption that leaves a marble-like pigmentation. The majority of cases have been found in Japan. Three new female. Sicilian patients with prurigo pigmentosa were studied. All of them had previously been diagnosed as having different types of dermatitis. The administration of minocycline, at a dosage of 100 mg/day for 1 month, induced the disappearance of the papular eruption and pruritus in two patients, with an improvement of the gross reticular pigmentation. The third showed no modifications of the clinical picture after 2 months of minocycline treatment, but her condition significantly improved after 1 month of treatment with diaminodiphenylsulfone, 100 mg/day. These observations allow us to suggest that prurigo pigmentosa might be relatively frequent but misdiagnosed in the Sicilian population.
色素性痒疹是一种丘疹性瘙痒性皮疹，会留下大理石样色素沉着。大多数病例发现于日本。对3名患有色素性痒疹的西西里女性患者进行了研究。她们之前均被诊断为患有不同类型的皮炎。2名患者服用米诺环素，剂量为每日100mg，持续1个月，丘疹性皮疹和瘙痒消失，网状色素沉着明显改善。第三名患者在米诺环素治疗2个月后临床症状未改善，但在服用氨苯砜（每日100mg）1个月后病情显著改善。这些观察结果使我们认为色素性痒疹在西西里人群中可能相对常见但易被误诊。
