急性睾酮对冠心病男性心肌缺血的影响。
Effect of acute testosterone on myocardial ischemia in men with coronary artery disease.
作者信息
Webb C M, Adamson D L, de Zeigler D, Collins P
机构信息
Cardiac Medicine, National Heart & Lung Institute, Imperial College School of Medicine, and Royal Brompton Hospital, London, United Kingdom.
出版信息
Am J Cardiol. 1999 Feb 1;83(3):437-9, A9. doi: 10.1016/s0002-9149(98)00880-7.
The effect of acute testosterone administration on exercise-induced myocardial ischemia was assessed in 14 men with coronary artery disease and low plasma testosterone concentrations in a study of randomized, double-blind, crossover design. Testosterone increased time to 1-mm ST-segment depression compared with placebo by 66 (15 to 117) seconds (p = 0.016), suggesting a beneficial effect of testosterone on myocardial ischemia in these patients.
在一项随机、双盲、交叉设计的研究中，对14名患有冠状动脉疾病且血浆睾酮浓度较低的男性，评估了急性给予睾酮对运动诱发心肌缺血的影响。与安慰剂相比，睾酮使出现1毫米ST段压低的时间增加了66（15至117）秒（p = 0.016），表明睾酮对这些患者的心肌缺血有有益作用。
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