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勃起功能障碍、代谢综合征与心血管风险:事实与争议

Erectile dysfunction, metabolic syndrome, and cardiovascular risks: facts and controversies.

作者信息

Sanchez Edward, Pastuszak Alexander W, Khera Mohit

机构信息

Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA.

Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA; Center for Reproductive Medicine, Baylor College of Medicine, Houston, TX, USA.

出版信息

Transl Androl Urol. 2017 Feb;6(1):28-36. doi: 10.21037/tau.2016.10.01.

DOI:10.21037/tau.2016.10.01
PMID:28217448
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5313297/
Abstract

Erectile dysfunction (ED) is the most common male sexual dysfunction, and shares many risk factors with systemic conditions including cardiovascular disease (CVD) and the metabolic syndrome (MetS). ED is considered to be an independent risk factor for CVD and can be a harbinger of future cardiovascular events. Given this relationship, each encounter for ED should be viewed by healthcare providers as an opportunity to screen for CVD and other comorbid conditions, including the MetS, that can significantly affect a man's overall health. While universally accepted screening guidelines are lacking, expert panels do recommend an approach to risk stratification in men with ED. In this review, we discuss the current state of understanding of the relationship between ED, the MetS, and CV risk, and how this impacts the approach to the patient presenting with ED.

摘要

勃起功能障碍(ED)是最常见的男性性功能障碍,与包括心血管疾病(CVD)和代谢综合征(MetS)在内的全身性疾病有许多共同的危险因素。ED被认为是CVD的独立危险因素,并且可能是未来心血管事件的先兆。鉴于这种关系,医疗保健提供者应将每次ED就诊视为筛查CVD和其他合并症(包括MetS)的机会,这些合并症会显著影响男性的整体健康。虽然缺乏普遍接受的筛查指南,但专家小组确实推荐了一种对ED男性进行风险分层的方法。在这篇综述中,我们讨论了目前对ED、MetS和心血管风险之间关系的理解现状,以及这如何影响对ED患者的处理方法。

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本文引用的文献

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The Association of Erectile Dysfunction and Cardiovascular Disease: A Systematic Critical Review.勃起功能障碍与心血管疾病的关联:一项系统性批判性综述。
Am J Mens Health. 2017 May;11(3):552-563. doi: 10.1177/1557988316630305. Epub 2016 Feb 4.
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Current Diagnosis and Management of Erectile Dysfunction.勃起功能障碍的当前诊断与管理
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Relationship between Serum Testosterone and Cardiovascular Disease Risk Determined Using the Framingham Risk Score in Male Patients with Sexual Dysfunction.血清睾酮与心血管疾病风险的关系——基于弗雷明汉风险评分在性功能障碍男性患者中的研究。
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Long-term testosterone treatment in elderly men with hypogonadism and erectile dysfunction reduces obesity parameters and improves metabolic syndrome and health-related quality of life.长期睾酮治疗可降低老年性腺功能减退伴勃起功能障碍患者的肥胖参数,改善代谢综合征和健康相关生活质量。
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Testosterone and the cardiovascular system: a comprehensive review of the clinical literature.睾酮与心血管系统:临床文献综述
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A systematic review of the association between erectile dysfunction and cardiovascular disease.一项关于勃起功能障碍与心血管疾病之间关联的系统综述。
Eur Urol. 2014 May;65(5):968-78. doi: 10.1016/j.eururo.2013.08.023. Epub 2013 Aug 23.
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Diabetes severity, metabolic syndrome, and the risk of erectile dysfunction.糖尿病严重程度、代谢综合征与勃起功能障碍风险。
J Sex Med. 2013 Dec;10(12):3102-9. doi: 10.1111/jsm.12318. Epub 2013 Sep 9.
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