Pokidysheva L N, Voronina F V, Khesin Ia E, Marchenko V I
Vopr Virusol. 1976 Sep-Oct(5):591-6.
When Krebs-2 ascitic carcinoma is transplanted to mice, administration of interferon may produce either a stimulating or an inhibiting effect on replication of carcinoma cells in the peritoneal cavity depending on the responsiveness of mice (intact or vaccinated with Newcastle disease virus) and the state of the transplanted cells ("common" or "tolerant"). Parallelism was observed in changes of the intensity of cell multiplications and indices of their enzymatic activity under the influence of exogenic interferon.
将克雷布斯-2腹水癌移植到小鼠体内时，根据小鼠的反应性（未处理或接种新城疫病毒）以及移植细胞的状态（“普通”或“耐受”），给予干扰素可能对腹腔内癌细胞的复制产生刺激或抑制作用。在外源性干扰素的影响下，观察到细胞增殖强度变化与其酶活性指标之间存在平行关系。
