Nene S, Moore W
Department of Surgery, UCLA School of Medicine, Los Angeles, CA 90095-6904, USA.
Ann Vasc Surg. 1999 Mar;13(2):169-73. doi: 10.1007/s100169900236.
The aim of this study was to determine the effect of primary closure versus patch angioplasty on the incidence of early recurrent stenosis after carotid endarterectomy in the hands of a single surgeon, and to analyze the risk factors associated with early recurrent stenosis after carotid endarterectomy. A retrospective review was performed of 178 consecutive patients who underwent 200 carotid endarterectomies-100 done consecutively with primary closure and 100 done consecutively with patch angioplasty. Of these patients, 126 qualified for analysis by having had at least 18 months of follow-up by serial duplex scanning. Of this group, the first 65 patients underwent 75 routine primary closures, while the last 61 underwent 67 routine patch angioplasties. All patients underwent a completion angiogram at the end of the case. Recurrent stenosis was defined as luminal diameter narrowing >60% on duplex scan. A multifactorial analysis was performed to analyze the effect of age, sex, tobacco use, diabetes, hypertension, peripheral vascular disease, coronary artery disease, and contralateral stenosis on recurrent stenosis. The results of this study showed that in a single surgeon's experience with carotid endarterectomy, varying only the method of closure between primary closure versus patch angioplasty, there is no statistically significant difference in the rate of early restenosis. No difference was noted in the perioperative morbidity and mortality between groups.
本研究的目的是确定在单一外科医生操作下,一期缝合与补片血管成形术对颈动脉内膜切除术后早期再发狭窄发生率的影响,并分析与颈动脉内膜切除术后早期再发狭窄相关的危险因素。对178例连续接受200次颈动脉内膜切除术的患者进行了回顾性研究,其中100例连续采用一期缝合,100例连续采用补片血管成形术。在这些患者中,126例通过连续双功扫描至少随访18个月而符合分析条件。在这组患者中,前65例患者接受了75次常规一期缝合,而后61例接受了67次常规补片血管成形术。所有患者在手术结束时均进行了血管造影检查。再发狭窄定义为双功扫描显示管腔直径狭窄>60%。进行多因素分析以分析年龄、性别、吸烟、糖尿病、高血压、外周血管疾病、冠状动脉疾病和对侧狭窄对再发狭窄的影响。本研究结果表明,在单一外科医生的颈动脉内膜切除术经验中,仅在一期缝合与补片血管成形术之间改变缝合方法,早期再狭窄率无统计学显著差异。两组之间围手术期发病率和死亡率无差异。