Freiha F, Mroueh A
West J Med. 1976 Dec;125(6):431-3.
Varicocele is an important cause of infertility in men. The exact mechanism by which varicocele depresses spermatogenesis is unknown but probably the retrograde flow of blood rich in catecholamines into the testes plays a major role. Because subfertile semen qualities are present in a large percentage of men with varicocele and because the response to surgical procedures is very good, high ligation of the left internal spermatic vein is recommended in men with varicocele and infertility.
精索静脉曲张是男性不育的一个重要原因。精索静脉曲张抑制精子发生的确切机制尚不清楚,但富含儿茶酚胺的血液逆行流入睾丸可能起主要作用。由于很大比例患有精索静脉曲张的男性精液质量欠佳,且对手术治疗的反应非常良好,因此建议对患有精索静脉曲张且不育的男性进行左侧精索内静脉高位结扎术。