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全程间歇短程化疗对新涂阳肺结核患者的长期疗效

[Long-term efficacy of full course intermittent short-course chemotherapy on new smear positive tuberculosis patients].

出版信息

Zhonghua Jie He He Hu Xi Za Zhi. 1997 Jun;20(3):164-6.

Abstract

OBJECTIVE

To evaluate the long-term efficacy of full course intermittent short-course chemotherapy [2H3R3Z3S3(E3)/4H3R3], which has first been used in the National Tuberculosis Control Programme with the loan from the World Bank and its satisfactory short-term efficacy has been achieved, on new smear positive tuberculosis patients.

METHOD

All new smear positive tuberculosis patients, registered by 56 counties of 12 project provinces and autonomous regions in 1992, were investigated to find out the bacteriological relapse rate 2 years after treatment.

RESULT

One hundred thirty five out of 4400 patients followed up were found smear positive, with a relapse rate of 3.1%.

CONCLUSION

The result suggests that the chemotherapy should be given a priority in the National Tuberculosis Control Programme because of its high cure rate.

摘要

目的

评估全程间歇短程化疗方案[2H3R3Z3S3(E3)/4H3R3]对新涂阳肺结核患者的长期疗效。该方案最初是在世界银行贷款支持的国家结核病防治项目中使用,已取得了令人满意的短期疗效。

方法

对1992年12个项目省和自治区的56个县登记的所有新涂阳肺结核患者进行调查,以了解治疗2年后的细菌学复发率。

结果

在4400例接受随访的患者中,有135例涂片阳性,复发率为3.1%。

结论

结果表明,由于该化疗方案治愈率高,应在国家结核病防治项目中优先使用。

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