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全程间歇短程化疗对新涂阳肺结核患者的长期疗效

[Long-term efficacy of full course intermittent short-course chemotherapy on new smear positive tuberculosis patients].

出版信息

Zhonghua Jie He He Hu Xi Za Zhi. 1997 Jun;20(3):164-6.

PMID:10072822
Abstract

OBJECTIVE

To evaluate the long-term efficacy of full course intermittent short-course chemotherapy [2H3R3Z3S3(E3)/4H3R3], which has first been used in the National Tuberculosis Control Programme with the loan from the World Bank and its satisfactory short-term efficacy has been achieved, on new smear positive tuberculosis patients.

METHOD

All new smear positive tuberculosis patients, registered by 56 counties of 12 project provinces and autonomous regions in 1992, were investigated to find out the bacteriological relapse rate 2 years after treatment.

RESULT

One hundred thirty five out of 4400 patients followed up were found smear positive, with a relapse rate of 3.1%.

CONCLUSION

The result suggests that the chemotherapy should be given a priority in the National Tuberculosis Control Programme because of its high cure rate.

摘要

目的

评估全程间歇短程化疗方案[2H3R3Z3S3(E3)/4H3R3]对新涂阳肺结核患者的长期疗效。该方案最初是在世界银行贷款支持的国家结核病防治项目中使用,已取得了令人满意的短期疗效。

方法

对1992年12个项目省和自治区的56个县登记的所有新涂阳肺结核患者进行调查,以了解治疗2年后的细菌学复发率。

结果

在4400例接受随访的患者中,有135例涂片阳性,复发率为3.1%。

结论

结果表明,由于该化疗方案治愈率高,应在国家结核病防治项目中优先使用。

相似文献

1
[Long-term efficacy of full course intermittent short-course chemotherapy on new smear positive tuberculosis patients].全程间歇短程化疗对新涂阳肺结核患者的长期疗效
Zhonghua Jie He He Hu Xi Za Zhi. 1997 Jun;20(3):164-6.
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[Effects of intermittent short-course chemotherapy under full-course supervision on the treatment of smear positive pulmonary tuberculosis].全程督导下间歇短程化疗对涂阳肺结核的治疗效果
Zhonghua Jie He He Hu Xi Za Zhi. 1996 Apr;19(2):104-6.
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[Efficacy of unfixed continuation phase short-course chemotherapy].
Zhonghua Jie He He Hu Xi Za Zhi. 1997 Dec;20(6):358-60.
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[Follow-up observation on relapse of smear negative pulmonary tuberculosis after short-course chemotherapy].[短程化疗后涂片阴性肺结核复发的随访观察]
Zhonghua Jie He He Hu Xi Za Zhi. 2003 Feb;26(2):74-6.
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Assessment of a combined preparation of isoniazid, rifampicin and pyrazinamide (Rifater) in the initial phase of chemotherapy in three 6-month regimens for smear-positive pulmonary tuberculosis: a five-year follow-up report.对异烟肼、利福平与吡嗪酰胺联合制剂(卫非特)在三种6个月疗程的涂阳肺结核化疗初始阶段的评估:一项五年随访报告
Int J Tuberc Lung Dis. 1999 Feb;3(2):126-32.
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[Analysis of short-term effects of short-course intermittent chemotherapies of the World Bank Loaned Project].
Zhonghua Jie He He Hu Xi Za Zhi. 1996 Dec;19(6):357-9.
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Long term follow up of HIV-infected patients with tuberculosis treated with 6-month intermittent short course chemotherapy.对接受6个月间歇短程化疗的HIV感染合并结核病患者的长期随访
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[Characteristics and treatment outcomes of INH-resistant or RFP-resistant tuberculosis].[耐异烟肼或耐利福平结核病的特征及治疗结果]
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[The short-term and long-term treatment outcomes in patients with pulmonary tuberculosis positive for drug-resistant and sensitive strains].[耐药和敏感菌株均呈阳性的肺结核患者的短期和长期治疗结果]
Zhonghua Jie He He Hu Xi Za Zhi. 2003 Feb;26(2):70-3.
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[Six-month short course chemotherapy containing pyrazinamide for initial treatment of pulmonary tuberculosis].含吡嗪酰胺的六个月短程化疗用于肺结核的初始治疗
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