Mo N, Li D
Department of Pharmacology, Guangxi Medical College, Nanninq, China.
Zhongguo Yao Li Xue Bao. 1997 Mar;18(2):124-7.
To study the effects of adrenoceptor agonists on the stellate ganglion neurons.
Intracellular recordings were made from neurons of the isolated rat stellate ganglia.
Noradrenaline and clonidine (10-30 mumol.L-1) reversibly depressed 3 types of calcium-dependent potentials, namely, the action potential shoulder; the spike after-hyperpolarization; the Ca2+ spike evoked in Krebs' solution containing TTX and TEA and fast excitatory postsynaptic potential (f-EPSP).
The adrenoceptor agonists inhibitied the 3 calcium-dependent potentials; f-EPSP was inhibited by reducing Ca2+ influx at presynaptic site in population of neurons.
研究肾上腺素能受体激动剂对星状神经节神经元的影响。
对分离的大鼠星状神经节神经元进行细胞内记录。
去甲肾上腺素和可乐定（10 - 30 μmol·L⁻¹）可逆性地抑制3种钙依赖性电位，即动作电位肩部、锋电位后超极化、在含TTX和TEA的 Krebs溶液中诱发的Ca²⁺锋电位以及快速兴奋性突触后电位（f-EPSP）。
肾上腺素能受体激动剂抑制了3种钙依赖性电位；f-EPSP是通过减少神经元群体突触前部位的Ca²⁺内流而被抑制的。
