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[接受非心脏手术的高危老年患者术后心脏发病率/死亡率]

[Postoperative cardiac morbidity/mortality in high-risk elderly patients undergoing non-cardiac surgery].

作者信息

de la Cruz Pérez C, Estecha Foncea M A, Cruz Mañas J, Castillo Caparrós A, Palma Pérez F, Sarmiento Pardo J

机构信息

Servicio de Anestesiología y Reanimación, Hospital Universitario Virgen de la Victoria, Málaga.

出版信息

Rev Esp Anestesiol Reanim. 1999 Jan;46(1):4-8.

Abstract

OBJECTIVE

To analyze cardiac morbidity and mortality after major noncardiac surgery in high-risk elderly patients.

PATIENTS AND METHOD

Retrospective study of patients 65 years old or older in the postoperative intensive care unit between January 1990 and September 1996, after major noncardiac surgery, with histories of known ischemic heart disease (IHD group) or with two or more coronary risk factors (CRF group). We analyzed age, number of risk factors, type of ischemic heart disease, type and nature of surgery and cardiac morbidity or mortality.

RESULTS

Five hundred twenty-nine patients were studied. Mean age was 72.1 +/- 5.1 years. The CRF group contained 366 patients (69.1%); the IHD group contained 163 (30.2%) patients with angina or histories of myocardial infarction. Rates of morbidity in the two groups were 10.1% and 25.8%, respectively (p < 0.001); the cardiac death rates were 2.18% and 5.5%, respectively (p = 0.08). No effect of number of coronary risk factors, type of ischemic heart disease, or type of surgery was found. Emergency surgery was associated with greater morbidity (p < or = 0.0011 and p < 0.001, respectively) and mortality (p < 0.001 in both groups). Age over 75 years was related to increased rates of morbidity (p = 0.003) and mortality (p = 0.031).

CONCLUSIONS

In our practice elderly patients with known ischemic heart disease undergoing major noncardiac surgery suffer more postoperative cardiac complications than do those who only have coronary risk factors. Mortality, however, is similar. The only factors associated with increased morbidity and mortality are emergency surgery and age over 75 years.

摘要

目的

分析高危老年患者非心脏大手术后的心脏发病率和死亡率。

患者与方法

对1990年1月至1996年9月在术后重症监护病房的65岁及以上患者进行回顾性研究,这些患者接受了非心脏大手术,有已知缺血性心脏病病史(缺血性心脏病组)或有两个或更多冠心病危险因素(冠心病危险因素组)。我们分析了年龄、危险因素数量、缺血性心脏病类型、手术类型和性质以及心脏发病率或死亡率。

结果

共研究了529例患者。平均年龄为72.1±5.1岁。冠心病危险因素组有366例患者(69.1%);缺血性心脏病组有163例(30.2%)有心绞痛或心肌梗死病史的患者。两组的发病率分别为10.1%和25.8%(p<0.001);心脏死亡率分别为2.18%和5.5%(p=0.08)。未发现冠心病危险因素数量、缺血性心脏病类型或手术类型有影响。急诊手术与更高的发病率(分别为p≤0.0011和p<0.001)和死亡率(两组均为p<0.001)相关。75岁以上的年龄与发病率(p=0.003)和死亡率(p=0.031)增加有关。

结论

在我们的实践中,已知患有缺血性心脏病的老年患者接受非心脏大手术后,术后心脏并发症比仅有冠心病危险因素的患者更多。然而,死亡率相似。与发病率和死亡率增加相关的唯一因素是急诊手术和75岁以上的年龄。

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