Kober G, Guldner N, Bussmann W D, Kaltenbach M
Z Kardiol. 1976 Nov;65(11):983-96.
In 58 patients (pts) with coronary heart disease volume parameters of both ventricles were determined from two angiograms . Four groups of pts were formed according to localization of left ventricular damage: group I (24 PTS) without myocardial infarction, group II (17 pts) with anterior wall infarction (AWI), group III (9pts) with inferior wall infarction (IWI), and group IV (8 pts) with AW and IWI. In group I enddiastolic volume (EDV) of the left ventricle (LV) was 135 +/- 61 ml/1.73 m2, of the right ventricle (RV) 145 +/- 62 ml/1.73 m2, the ejection fraction (EF) 74% (LV) and 66% (RV). In group II EDV of LV increased significantly (194 +/- 88) and EF decreased to 50%, whereas EDV and EF of RV remaine unchanged. In group III EDV (LV 160 +/- 46, RV 172 +/- 95) of both ventricles was increased and EF (LV 57%, RV 58%) decreased, In group IV a more pronounced increase in EDV (LV 218 +1- 58, RV 181 +/- 30) and decrease in EF (LV 46%, RV 48%) was seen. A disturbance in contraction of RV was observed only in cases with IWI of LV. In contrast to LV, a diffuse impairment of RV occured. It was assumed that in RV disturbances in contraction exceeded the extent of scarred areas which might be explained by partially reversible ischemic disturbances of function.
对58例冠心病患者，通过两次血管造影确定双心室的容积参数。根据左心室损害的部位将患者分为四组：第一组（24例）无心肌梗死；第二组（17例）有前壁梗死（AWI）；第三组（9例）有下壁梗死（IWI）；第四组（8例）有前壁和下壁梗死。第一组左心室（LV）舒张末期容积（EDV）为135±61ml/1.73m²，右心室（RV）为145±62ml/1.73m²，射血分数（EF）左心室为74%，右心室为66%。第二组左心室EDV显著增加（194±88），EF降至50%，而右心室EDV和EF保持不变。第三组双心室EDV（左心室160±46，右心室172±95）均增加，EF（左心室57%，右心室58%）降低。第四组EDV增加更明显（左心室218±58，右心室181±30），EF降低（左心室46%，右心室48%）。仅在左心室有下壁梗死的病例中观察到右心室收缩障碍。与左心室不同，右心室出现弥漫性损害。据推测，右心室收缩障碍超过了瘢痕区域的范围，这可能是由部分可逆的缺血性功能障碍所解释。
