Sander P, Thyssen H, Lose G, Andersen J T
Incontinence Clinic, Department of Urology, Hvidovre Hospital, University of Copenhagen, Denmark.
Obstet Gynecol. 1999 Mar;93(3):407-11. doi: 10.1016/s0029-7844(98)00411-6.
To assess the effect of a vaginal device (Continence Guard) on urine leakage and quality of life.
Fifty-five women with stress incontinence participated in a 3-month study. They were assessed by the Incontinence Impact Questionnaire, two incontinence-related quality-of-life questions, a generic quality-of-life questionnaire (Short Form-36), two 24-hour home pad weighing tests, a 2-day voiding diary, uroflowmetry, urine cultures, and a questionnaire about subjective effectiveness of the device.
Forty-one (74.5%) women completed the study. Estimated on an intent-to-treat basis, the vaginal device was associated with subjective cure in 11 women (20%) and improvement in 27 (49%). The mean 24-hour pad test leakage and leakage episodes in the voiding diary decreased significantly. Fifty-eight percent of the 55 women enrolled wanted to continue using the device after 3 months. The quality of life measured by the Incontinence Impact Questionnaire showed highly significant improvement, and the results of the two incontinence-related quality of life questions also showed significant improvement. Responses to the Short Form-36 general health questionnaire showed no significant changes. Improvement on the Incontinence Impact Questionnaire correlated with improvements in incontinence, whereas the Short Form-36 scores were unchanged.
Treatment with the Continence Guard significantly decreases leakage and improves quality of life in women with symptoms of urinary stress incontinence. An incontinence-specific, rather than a generic, quality-of-life questionnaire was important in assessing treatment outcomes.
评估一种阴道装置（尿失禁防护器）对尿失禁及生活质量的影响。
55名压力性尿失禁女性参与了一项为期3个月的研究。通过尿失禁影响问卷、两个与尿失禁相关的生活质量问题、一份通用生活质量问卷（简短健康调查问卷-36）、两次24小时家庭尿垫称重测试、一份为期两天的排尿日记、尿流率测定、尿培养以及一份关于该装置主观有效性的问卷对她们进行评估。
41名（74.5%）女性完成了研究。基于意向性分析，该阴道装置使11名女性（20%）主观治愈，27名女性（49%）病情改善。24小时尿垫测试的平均漏尿量及排尿日记中的漏尿次数显著减少。55名入组女性中有58%希望在3个月后继续使用该装置。尿失禁影响问卷所衡量的生活质量有极显著改善，两个与尿失禁相关的生活质量问题的结果也有显著改善。简短健康调查问卷-36一般健康问卷的回答无显著变化。尿失禁影响问卷的改善与尿失禁情况的改善相关，而简短健康调查问卷-36的得分未变。
使用尿失禁防护器治疗可显著减少有压力性尿失禁症状女性的漏尿并改善其生活质量。在评估治疗效果时，一份针对尿失禁的而非通用的生活质量问卷很重要。
