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[类癌样畸形问题]

[The problem of sirenoid malformation].

作者信息

Anton W, Stanulla H, Riefenstahl M

出版信息

Zentralbl Gynakol. 1976;98(22):1394-400.

PMID:1007701
Abstract

The pathological-anatomical and radiological findings of the rare sirenoid malformations which have to be assigned to the disturbed developments of the candal vertebral column section are discussed taking a female apodal sirenomelus involving agenesia of a large part of the intestine and the urogenital tract. About 330 cases have been dealt with in international publications. Exogenic factors are in the foreground, mainly hypoxemic conditions during the embryogenesis whereas heritability is apparently not given.

摘要

本文以一名患有大部分肠道和泌尿生殖道发育不全的女性无足并腿畸形为例,讨论了罕见的尾状脊柱节段发育异常的病理解剖学和放射学表现。国际出版物中已报道了约330例此类病例。外源性因素是主要原因,主要是胚胎发育期间的低氧状况,而遗传因素显然不存在。

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