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二尖瓣前叶乳头肌纤维弹性瘤的修复:两例病例描述及文献综述

Mitral valve repair for anterior leaflet papillary fibroelastoma: two case descriptions and a literature review.

作者信息

Di Mattia D G, Assaghi A, Mangini A, Ravagnan S, Bonetto S, Fundarò P

机构信息

Department of Thoracic and Cardiovascular Surgery, Luigi Sacco Hospital, Milan, Italy.

出版信息

Eur J Cardiothorac Surg. 1999 Jan;15(1):103-7. doi: 10.1016/s1010-7940(98)00271-1.

DOI:10.1016/s1010-7940(98)00271-1
PMID:10077384
Abstract

Cardiac papillary fibroelastomas are rare cardiac tumors and have been considered a 'benign' incidental finding that may have significant clinical manifestations. In this paper we report two cases of mitral valve fibroelastoma: one was discovered by chance with transthoracic echocardiography in a young healthy man, the other was an intraoperative incidental finding in a middle aged man with a recent history of acute myocardial infarction. The mitral valve was repaired in both cases after excising the tumor. The patients did well and remain asymptomatic. A literature review was compiled which comprises previous case reports of 34 patients with mitral valve papillary fibroelastomas. Most were asymptomatic, but when symptoms occurred, they could be disabling, such as stroke, cardiac heart failure, myocardial infarction, and sudden death. Papillary fibroelastoma is amenable to simple surgical excision or in addition to mitral valve repair or replacement. Recurrence has not been reported.

摘要

心脏乳头肌弹性纤维瘤是一种罕见的心脏肿瘤,一直被认为是一种“良性”的偶然发现,但可能具有显著的临床表现。在本文中,我们报告了两例二尖瓣弹性纤维瘤病例:一例是在一名年轻健康男性中通过经胸超声心动图偶然发现的,另一例是在一名近期有急性心肌梗死病史的中年男性手术中偶然发现的。两例均在切除肿瘤后对二尖瓣进行了修复。患者情况良好,仍无症状。我们对文献进行了综述,其中包括之前34例二尖瓣乳头肌弹性纤维瘤患者的病例报告。大多数患者无症状,但出现症状时可能会导致残疾,如中风、心力衰竭、心肌梗死和猝死。乳头肌弹性纤维瘤适合简单的手术切除,或者除了二尖瓣修复或置换之外还可进行该手术。尚未有复发的报道。

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引用本文的文献

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Tumoration in Anterior Leaflet of the Mitral Valve.二尖瓣前叶肿瘤形成
Braz J Cardiovasc Surg. 2021 Feb 1;36(1):116-119. doi: 10.21470/1678-9741-2020-0557.
2
Thrombus or tumor? a case of fibroelastoma as indicated during the submission process.血栓还是肿瘤?提交过程中显示的一例纤维弹性瘤病例。
Cases J. 2009 Jan 8;2(1):31. doi: 10.1186/1757-1626-2-31.
3
Papillary fibroelastoma of the mitral valve associated with rheumatic mitral valve stenosis.二尖瓣乳头肌弹力纤维瘤合并风湿性二尖瓣狭窄。
Jpn J Thorac Cardiovasc Surg. 2005 Mar;53(3):143-6. doi: 10.1007/s11748-005-0020-z.