Strizhakov A N, Musaev Z M
Vestn Ross Akad Med Nauk. 1999(1):51-7.
A total of 810 pregnant women were examined in order to elucidate the pathogenesis of hemodynamic disorders in gestosis. The main group consisted of 460 patients with gestosis of different severity and the control group included 150 women with uneventful pregnancy. Central and regional hemodynamics in normal pregnancy were studied in detail by modern diagnostic methods (echocardiography and dopplerometry) and the relationship between the detected shifts and the function of the utero-placento-fetal circulation was shown. The predominant type of central hemodynamics in gestosis is the hypokinetic. Disorders in renal and cerebral circulation contribute to the pathogenesis of severe gestosis. Pathogenetic variants of hemodynamics shifts in gestosis are analyzed and recommendations on the follow-up of pregnancy are offered. Indications for preterm delivery in the interests of the mother and fetus are defined.
为阐明妊娠中毒症血流动力学紊乱的发病机制，共对810名孕妇进行了检查。主要组由460例不同严重程度的妊娠中毒症患者组成，对照组包括150例妊娠正常的妇女。采用现代诊断方法（超声心动图和多普勒测量法）详细研究了正常妊娠时的中心和区域血流动力学，并显示了检测到的变化与子宫-胎盘-胎儿循环功能之间的关系。妊娠中毒症时中心血流动力学的主要类型是运动减弱型。肾循环和脑循环紊乱促成了严重妊娠中毒症的发病机制。分析了妊娠中毒症血流动力学变化的发病机制变体，并提出了妊娠随访建议。确定了为母婴利益而行早产的指征。
