Argento C, Fernández Mendy J, Cosentino M J
Instituto de la Visión, Buenos Aires, Argentina.
J Cataract Refract Surg. 1999 Mar;25(3):374-82. doi: 10.1016/s0886-3350(99)80086-8.
To analyze the effectiveness of laser in situ keratomileusis (LASIK) and arcuate keratotomy (AK) to treat simple myopic, compound myopic, and mixed astigmatism.
Instituto de la Visión, Buenos Aires, Argentina.
This retrospective nonrandomized study comprised 821 cases treated with LASIK and 46 cases treated with AK. Patients were divided into 4 groups, which had the following preoperative cylinder corrections: simple myopic astigmatism (Group 1) (LASIK: n = 76, -3.91 diopters [D] +/- 1.29 [SD]; AK: n = 5, -3.85 +/- 0.65 D); compound myopic astigmatism up to 2.00 D (Group 2) (LASIK: n = 401, -1.69 +/- 0.76 D; AK: n = 14, -1.48 +/- 0.41 D); compound myopic astigmatism over 2.00 D (Group 3) (LASIK: n = 253, -3.61 +/- 0.89 D; AK: n = 16, -3.09 +/- 0.84 D); mixed astigmatism (Group 4) (LASIK: n = 91, +3.65 +/- 1.62 D; AK: n = 11, 4.39 +/- 0.92 D).
Six months postoperatively, the cylinder's vector-corrected change was as follows: Group 1, LASIK 3.75 +/- 1.08 D, AK 3.16 +/- 0.84 D; Group 2, LASIK 1.55 +/- 1.12 D, AK 1.34 +/- 0.44 D; Group 3, LASIK 3.39 +/- 0.98 D, AK 2.70 +/- 1.21 D; Group 4, LASIK 3.77 +/- 1.43 D, AK 3.75 +/- 0.89 D. Respective mean uncorrected visual acuities in each group were as follows: Group 1, 0.71 +/- 0.12 and 0.60 +/- 0.12; Group 2, 0.83 +/- 0.12 and 0.78 +/- 0.24; Group 3, 0.78 +/- 0.18 and 0.48 +/- 0.24; Group 4, 0.69 +/- 0.21 and 0.55 +/- 0.18.
The vector-corrected change and visual acuity achieved with LASIK were better, although not significantly, than those attained with AK except for the UCVA obtained with LASIK in eyes with compound myopic astigmatism over 2.00 D. Both methods proved to be safe.
分析准分子原位角膜磨镶术（LASIK）和弧形角膜切开术（AK）治疗单纯性近视、复合性近视和混合性散光的有效性。
阿根廷布宜诺斯艾利斯视觉研究所。
这项回顾性非随机研究包括821例行LASIK治疗的病例和46例行AK治疗的病例。患者被分为4组，其术前柱镜矫正情况如下：单纯性近视散光（第1组）（LASIK：n = 76，-3.91屈光度[D]±1.29[标准差]；AK：n = 5，-3.85±0.65 D）；复合性近视散光达2.00 D（第2组）（LASIK：n = 401，-1.69±0.76 D；AK：n = 14，-1.48±0.41 D）；复合性近视散光超过2.00 D（第3组）（LASIK：n = 253，-3.61±0.89 D；AK：n = 16，-3.09±0.84 D）；混合性散光（第4组）（LASIK：n = 91，+3.65±1.62 D；AK：n = 11，4.39±0.92 D）。
术后6个月，柱镜矢量校正后的变化如下：第1组，LASIK为3.75±1.08 D，AK为3.16±0.84 D；第2组，LASIK为1.55±1.12 D，AK为1.34±0.44 D；第3组，LASIK为3.39±0.98 D，AK为2.70±1.21 D；第4组，LASIK为3.77±1.43 D，AK为3.75±0.89 D。每组各自的平均未矫正视力如下：第1组，0.71±0.12和0.60±0.12；第2组，0.83±0.12和0.78±0.24；第3组，0.78±0.18和0.48±0.24；第4组，0.69±0.21和0.55±0.18。
LASIK实现的矢量校正变化和视力比AK更好，尽管差异不显著，但2.00 D以上复合性近视散光眼LASIK的最佳矫正视力除外。两种方法均证明是安全的。
