Therapeutic agent for treating dysuria (NC-1800): absolute configuration of the enantiomers.
作者信息
Yoshida S, Yamamoto M, Aoki Y, Nohira H
机构信息
Department of Applied Chemistry, Faculty of Engineering, Saitama University, Japan.
出版信息
Chirality. 1999;11(3):256-60. doi: 10.1002/(SICI)1520-636X(1999)11:3<256::AID-CHIR13>3.0.CO;2-#.
Abstract
The absolute configuration of an enantiomer of the title compound, (+/-)-1. fumaric acid salt, was determined by X-ray crystallographic analysis of (+)-1 [salt of (+)-tartaric acid [(+)-2]]. This salt for X-ray crystallographic analysis was prepared by a simple method. The analysis of (+)-1 [salt of (+)-2] showed that this enantiomer has the 5-S and 1-R absolute configuration. The final R and Rw values were 0.0614 and 0.0713, respectively.
摘要
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