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[EGF-dependent association of 20S-proteasome and alpha-RNP particles with the epidermal growth factor receptor in A-431 cells].

作者信息

Konstantinova I M, Wetzker R, Burova E B, Vasilenko K P, Turoverova L V, Volkova I V, Ivanova V A, Teslenko L V, Nikol'skiĭ N N

机构信息

Institute of Cytology, Russian Academy of Sciences, St. Petersburg.

出版信息

Tsitologiia. 1998;40(11):954-7.

PMID:10081090
Abstract

Here we demonstrate that the epidermal growth factor (EGF) induces association of prosomes (20S-proteasomes) with its receptor in A-431 cells. Additionally, ligand-dependent association of ribonucleoprotein particles (alpha-RNP), containing small ALU-like RNA, with the EGF receptor was demonstrated. A suggestion has been put forward on the involvement of prosomes and alpha-RNP in the EGF signal transmission to different stages of gene expression.

摘要

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