Bloomston M, D'Angelo P, Galliano D, Butler J, Dean R, Rosemurgy A S
University of South Florida College of Medicine, Tampa, USA.
Ann Surg Oncol. 1999 Mar;6(2):195-9. doi: 10.1007/s10434-999-0195-0.
Needle localization and excision have been the preferred techniques for treating nonpalpable mammographic abnormalities. Recently, a less invasive approach, using the Advanced Breast Biopsy Instrumentation (ABBI) system, was introduced. This study was undertaken to determine the feasibility, utility, and cost of this new alternative approach.
Between April 1996 and May 1997, 100 consecutive women underwent excisional breast biopsies using the ABBI system. Demographic information, mammographic findings, pathological findings, hospital/professional fees, complications, and subsequent interventions were documented.
Excisional biopsies using the ABBI system were successful for 99 women (average age, 62 years; range, 34-87 years). Of the 99 lesions removed with the ABBI system, 27 were microcalcifications, 60 were suspicious solid nodules, and 12 were nodules with microcalcifications. The ABBI system was used in an outpatient surgical setting, with only one patient requiring sedation (because of anxiety). Cancer was seen in the biopsy specimens for 18 patients, seven of whom (35%) exhibited no residual tumor at the time of definitive treatment. Postoperative hematomas occurred in two patients; one hematoma required surgical drainage. One missed cancer was detected in follow-up mammograms 6 months after biopsy. The total average procedural cost was $3406.44 +/- 486.63.
Excisional breast biopsy using the ABBI system is an effective diagnostic method. It has a low complication rate, and its cost is comparable to that of classical needle localization.
针定位切除一直是治疗乳腺钼靶检查发现的不可触及异常的首选技术。最近，一种侵入性较小的方法——使用先进乳腺活检器械（ABBI）系统被引入。本研究旨在确定这种新的替代方法的可行性、实用性和成本。
在1996年4月至1997年5月期间，100名连续的女性使用ABBI系统接受了乳腺切除活检。记录了人口统计学信息、乳腺钼靶检查结果、病理检查结果、医院/专业费用、并发症及后续干预情况。
使用ABBI系统进行的切除活检对99名女性（平均年龄62岁；范围34 - 87岁）成功。在通过ABBI系统切除的99个病灶中，27个为微钙化，60个为可疑实性结节，12个为伴有微钙化的结节。ABBI系统用于门诊手术，只有1名患者因焦虑需要镇静。活检标本中发现癌症的有18名患者，其中7名（35%）在确定性治疗时无残留肿瘤。术后有2名患者出现血肿；其中1例血肿需要手术引流。活检后6个月的随访乳腺钼靶检查中发现1例漏诊癌症。总平均手术成本为3406.44美元±486.63美元。
使用ABBI系统进行乳腺切除活检是一种有效的诊断方法。它的并发症发生率低，且成本与传统针定位相当。
