通过向输精管注射化学药剂诱导雄性大鼠不育。
Sterility induced in male rats by injection of chemical agents into the vas deferens.
作者信息
Raman G, Purandare T V, Munshi S R
出版信息
Andrologia. 1976;8(4):321-5. doi: 10.1111/j.1439-0272.1976.tb01663.x.
Abstract
Changes in the histopathology of the testes with the epididymis were studied 3 months and 6 months after vasocclusion either with ethanol urea mixture or ethanol alone in male rats. A gradual decrease in the fertility of treated animals was observed. The epididymis showed tubules with sperm granuloma and the testis showed empty tubules with Leydig cell hyperplasia in the urea-ethanol treated animals.
摘要
在雄性大鼠中，研究了用乙醇尿素混合物或单独用乙醇进行输精管阻塞后3个月和6个月时睾丸与附睾的组织病理学变化。观察到处理组动物的生育能力逐渐下降。在尿素 - 乙醇处理的动物中，附睾显示有精子肉芽肿的小管，睾丸显示有空的小管和间质细胞增生。
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