Vilde F, Nezelof C
Ann Anat Pathol (Paris). 1976 Jan-Feb;21(1):59-74.
The lesions seen in chronic familial granulomatosis are variable and seen in varied combinations: granulomas, often disseminated, pseudotuberculous lesions, histiocytes with a high content in lipofuscins seen in the liver, lymph nodes, spleen and lungs in particular. These lesions may be explained at least in part by a congenital defect in leucocytes, which is peculiar to this hereditary disease, and which concernes bactericidal functions.
慢性家族性肉芽肿病中所见的病变多种多样，且以不同组合出现：肉芽肿，常为播散性，假结核性病变，特别是在肝脏、淋巴结、脾脏和肺中可见含高量脂褐素的组织细胞。这些病变至少部分可由白细胞的先天性缺陷来解释，这种缺陷是这种遗传性疾病所特有的，且与杀菌功能有关。
