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[围产期病史、精神运动发育迟缓、学习困难及家族史。它们是癫痫的危险因素吗?]

[Perinatal antecedents, psychomotor retardation, learning difficulties and family history. Are they a risk factor for epilepsy?].

作者信息

Martínez Menéndez B, Simón de las Heras R, de la Peña Mayor P, Pérez Sempere A, Alvarez Tejerina J, Mateos Beato F

机构信息

Unidad de Neurología Pediátrica, H. Universitario de Getafe, Madrid.

出版信息

An Esp Pediatr. 1999 Jan;50(1):49-51.

Abstract

OBJECTIVE

Epilepsy has been associated with certain circumstances such as perinatal pathology, learning difficulties, head trauma, infections of the central nervous system, febrile seizures and family history of epilepsy. The objective of our study was to analyze the association of the mentioned circumstances with epilepsy in a group of children with generalized spike-wave (S-W) in the electroencephalogram (EEG).

PATIENTS AND METHODS

One hundred seventy pediatric patients with, S-W were found from a register of 39,322 consecutive EEGs. The patients were classified into 2 groups: epileptic and non-epileptic. Both groups were compared for the presence of known risk factors of epilepsy.

RESULTS

Of the 170 patients, 154 (90.6%) were epileptic and 16 (9.4%) were not. Mean follow-up was 4.5 years. Neither past medical antecedents nor family history was found to be associated with epilepsy.

CONCLUSIONS

The risk of epilepsy in children with S-W in the EEG is not associated with problems in pregnancy, the birth or neonatal period, learning difficulties or family history of epilepsy.

摘要

目的

癫痫与某些情况相关,如围产期病理状况、学习困难、头部外伤、中枢神经系统感染、热性惊厥以及癫痫家族史。我们研究的目的是分析上述情况与一组脑电图(EEG)显示有广泛性棘波(S-W)的儿童癫痫之间的关联。

患者与方法

从连续39322份脑电图记录中找出170例有S-W的儿科患者。将患者分为两组:癫痫组和非癫痫组。比较两组中已知的癫痫危险因素。

结果

170例患者中,154例(90.6%)为癫痫患者,16例(9.4%)不是。平均随访时间为4.5年。既往病史和家族史均未发现与癫痫有关。

结论

脑电图显示有S-W的儿童患癫痫的风险与妊娠、出生或新生儿期问题、学习困难或癫痫家族史无关。

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