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[Synthesis of substituted benzoylacrylic acids as potential antagonists of phospholipase A2].

作者信息

Nuhn P, Herrmann A, Radman M

机构信息

Institut für Pharmazeutische Chemie, Martin-Luther-Universität, Halle, Germany.

出版信息

Pharmazie. 1999 Feb;54(2):93-8.

PMID:10084154
Abstract

Long chain alkylbenzenes were acylated with maleic anhydride and substituted maleic anhydrides. The resulting benzoyl acrylic acids were tested on phospholipase A2. The isomeric ratio (Z/E) of the benzoyl acrylic acids was estimated by NMR spectroscopy. A few acrylic acids cyclized to hydroxybutenolids.

摘要

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