Orias M, Mahnensmith R L, Perazella M A
Section of Nephrology, Yale University School of Medicine, New Haven, Conn., USA.
Am J Nephrol. 1999;19(1):60-3. doi: 10.1159/000013427.
Phosphate intoxication, manifested by hypocalcemic tetany and acute renal failure, may complicate bowel-cleansing preparations which contain phosphate. These preparations are commonly used to prepare patients for various gastrointestinal procedures. Often, patients who receive these regimens are at increased risk of phosphate intoxication from diseases which slow gastrointestinal transit or decrease renal excretion (renal insufficiency). We present a patient who developed oliguric acute renal failure from severe phosphate intoxication associated with a phosphate-containing bowel-cleansing regimen.
以低钙血症性手足搐搦和急性肾衰竭为表现的磷酸盐中毒,可能会使含磷酸盐的肠道清洁制剂变得复杂。这些制剂常用于让患者为各种胃肠道手术做准备。通常,接受这些方案的患者因胃肠道蠕动减慢或肾排泄减少(肾功能不全)的疾病而发生磷酸盐中毒的风险增加。我们报告一名患者,其因与含磷酸盐的肠道清洁方案相关的严重磷酸盐中毒而发生少尿性急性肾衰竭。