Solodky A, Assali A, Herz I, Hasdai D, Kusniec J, Sulkes J, Sclarovsky S, Birnbaum Y
Department of Cardiology and Epidemiology Unit, Rabin Medical Center, Petah Tiqva, Israel.
Cardiology. 1998;90(4):274-9. doi: 10.1159/000006858.
This study assessed the ability of simple clinical and electrocardiographic (ECG) variables routinely obtained on admission to identify patients with inferior myocardial infarction who are at high risk of developing high-degree atrioventricular (AV) block within the first 24 h of hospitalization in 205 patients. The admission ECGs were classified into two patterns based on the J-point to R-wave amplitude ratio: pattern 1: those with J-point/R-wave ratio <0.5; pattern 2: patients with J-point/R-wave ratio >/=0.5 in >/=2 inferior leads (II, III and aVF). High-degree AV block was found in 10.2% of the patients (21 of 205 patients; 5 and 16% of the patients with initial patterns 1 and 2, respectively, p = 0.014). Multivariate logistic regression analysis revealed that the only variables independently associated with high-degree AV block were the initial ECG pattern 2 versus 1 (odds ratio, OR, 4.47, 95% confidence interval, CI, 1.18-16.9; p = 0.0276), age (OR 1.06, 95% CI 1.01-1.12; p = 0.0254); Killip class >1 (OR 2.33, CI 0.83-6. 54; p = 0.1065) and thrombolytic therapy (OR 0.32, 95% CI 0.11-0.93; p = 0.037).
本研究评估了在205例患者入院时常规获取的简单临床和心电图(ECG)变量,以识别下壁心肌梗死患者中在住院后24小时内发生高度房室(AV)传导阻滞的高危患者。根据J点至R波振幅比值,将入院心电图分为两种类型:类型1:J点/R波比值<0.5者;类型2:在≥2个下壁导联(II、III和aVF)中J点/R波比值≥0.5的患者。10.2%的患者发生了高度AV传导阻滞(205例患者中有21例;初始类型1和类型2的患者分别为5%和16%,p = 0.014)。多因素logistic回归分析显示,与高度AV传导阻滞独立相关的唯一变量是初始心电图类型2与类型1(比值比,OR,4.47,95%置信区间,CI,1.18 - 16.9;p = 0.0276)、年龄(OR 1.06,95% CI 1.01 - 1.12;p = 0.0254);Killip分级>1(OR 2.33,CI 0.83 - 6.54;p = 0.1065)和溶栓治疗(OR 0.32,95% CI 0.11 - 0.93;p = 0.037)。