Topuzov E G, Beliakov N A, Solomennikov A V, Kokaia A A, Bondarchuk D M, Shishkina G A
I.I. Mechnikov State Medical Academy, St. Petersburg.
Vopr Onkol. 1998;44(6):708-10.
The data on treatment 84 patients with large bowel carcinoma aggravated by occlusion ileus are discussed. The study group included 49 patients who received intraoperative sorption dialysis of large bowel (ISDLB). Intraoperative lavage of large bowel (ILLB) was given to 35 patients who were in control. A significantly higher detoxication effect of ISDLB was recorded by hematological and biochemical index dynamics analysis. Lethality dropped to 6% in the group receiving ISDLB (11%). The latter patients spent 15 +/- 4 days in hospital as compared to 25 +/- 4 days in control. The postoperative complication rates were 14 and 29%, respectively. ISDLB should be indicated in complex therapy of bowel carcinoma aggravated by occlusion ileus because of its cleansing effect which significantly reduces end-genuous intoxication.
本文讨论了84例因肠梗阻加重的大肠癌患者的治疗数据。研究组包括49例接受大肠术中吸附透析（ISDLB）的患者。对照组35例患者接受大肠术中灌洗（ILLB）。通过血液学和生化指标动态分析，记录到ISDLB具有显著更高的解毒效果。接受ISDLB的组死亡率降至6%（对照组为11%）。与对照组的25±4天相比，后一组患者住院时间为15±4天。术后并发症发生率分别为14%和29%。由于其清洁作用可显著降低内源性中毒，ISDLB应被用于肠梗阻加重的大肠癌综合治疗中。
