Bischoff H, Freitag P, Jundt G, Steinmann B, Tyndall A, Theiler R
Department of Rheumatology, University Hospital Basel, Switzerland.
Clin Rheumatol. 1999;18(1):48-51. doi: 10.1007/s100670050052.
A 65-year-old woman presented with vertebral fractures of the lumbar spine and a history of pathological fractures following minor trauma, which had occurred before the onset of menopause. Her past medical history was significant for intermittent low back pain since childhood, which was attributed to thoracolumbar scoliosis. A diagnosis of unclassifiable osteoporosis was made until invasive diagnostic procedures suggested a mild form of type I osteogenesis imperfecta (OI). In unclear or atypical perimenopausal osteoporosis and diagnosis of OI should be considered.
一名65岁女性因腰椎椎体骨折就诊，有轻微外伤后发生病理性骨折的病史，这些骨折发生在绝经前。她既往有自幼间歇性腰痛的病史，归因于胸腰椎脊柱侧弯。在侵入性诊断程序提示为轻度I型成骨不全（OI）之前，诊断为无法分类的骨质疏松症。对于不明原因或非典型的围绝经期骨质疏松症，应考虑OI的诊断。
