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成人骨多灶性嗜酸性肉芽肿的发病:多种治疗选择及自发愈合评估的长期随访

Adult onset of multifocal eosinophilic granuloma of bone: a long-term follow-up with evaluation of various treatment options and spontaneous healing.

作者信息

Boutsen Y, Esselinckx W, Delos M, Nisolle J F

机构信息

Department of Rheumatology, Louvain University Hospital in Mont-Godinne, Yvoir, Belgium.

出版信息

Clin Rheumatol. 1999;18(1):69-73. doi: 10.1007/s100670050058.

DOI:10.1007/s100670050058
PMID:10088957
Abstract

We report a case of multifocal-monosystemic Langerhans cell histiocytosis (LCH), formerly usually referred to as eosinophilic granuloma (EG) of bone. The condition developed in a 36-year-old man. A notable infrequent thoracic spine location and two successive distinct costal lesions were observed. Both the first costal site and the vertebral location healed spontaneously; the second costal lesion underwent biopsy resection. The patient's disease course with an 8-year follow-up is discussed with reference to various treatment options, emphasising in selected cases a watchful conservative approach, in view of the widely documented potential for spontaneous healing.

摘要

我们报告一例多灶性单系统朗格汉斯细胞组织细胞增多症(LCH),以前通常称为骨嗜酸性肉芽肿(EG)。该病例发生在一名36岁男性身上。观察到一个不常见的胸椎部位以及两个连续的不同肋骨病变。第一肋骨部位和椎体部位均自行愈合;第二个肋骨病变进行了活检切除。结合各种治疗选择讨论了该患者长达8年随访的病程,鉴于有大量文献记载的自发愈合可能性,在某些病例中强调了谨慎的保守方法。

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