Wei A, Smallwood A, Alexander R S, Duke J, Ross H, Rosenfeld S A, Chang C H
Department of Chemical and Physical Sciences, The DuPont Pharmaceuticals Company, DuPont Experimental Station, PO Box 80353, Wilmington, DE 19880, USA.
Acta Crystallogr D Biol Crystallogr. 1999 Apr;55(Pt 4):862-4. doi: 10.1107/s0907444998017673.
The complex of bovine factor Xa and recombinant tick anticoagulant peptide (rTAP) was crystallized in two different crystal forms using polyethylene glycol as a precipitant. Form I belongs to space group P42212 with unit-cell dimensions a = b = 133.1, c = 68.8 A. It contains one complex per asymmetric unit and diffracts to 3.0 A resolution. Form II belongs to P41212 (or P43212) with dimensions a = b = 126.5, c = 146.7 A; it contains two complexes per asymmetric unit and diffracts to 2.5 A. The crystals of both forms consist of factor Xa (MW = 45.3 kDa) and rTAP (MW = 6.7 kDa).
