Logan J M, Orange G V, Maggs A F
Department of Medical Microbiology, University of Dundee Medical School, Ninewells Hospital, UK.
J Infect. 1999 Jan;38(1):45-7. doi: 10.1016/s0163-4453(99)90030-0.
We report the case of a young man who apparently suffered successive episodes of meningitis and cerebral abscess over a 1-month period, both of which were diagnosed by two different molecular approaches; PCR for Neisseria meningitidis IS1106 from CSF and 16S rRNA gene sequencing on a specimen of brain pus. In each case, cultures were negative due to prior antibiotic therapy.
我们报告了一名年轻男性的病例，他在1个月内明显连续发生脑膜炎和脑脓肿，这两种疾病均通过两种不同的分子方法诊断；一种是对脑脊液进行PCR检测脑膜炎奈瑟菌IS1106，另一种是对脑脓肿标本进行16S rRNA基因测序。在每种情况下，由于先前使用过抗生素治疗，培养结果均为阴性。
