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BRCA1 and BRCA2 testing: weighing the demand against the benefits.

作者信息

Devilee P

出版信息

Am J Hum Genet. 1999 Apr;64(4):943-8. doi: 10.1086/302350.

DOI:10.1086/302350
PMID:10090879
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1377818/
Abstract
摘要

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BRCA1 and BRCA2 testing: weighing the demand against the benefits.BRCA1和BRCA2检测:权衡需求与益处。
Am J Hum Genet. 1999 Apr;64(4):943-8. doi: 10.1086/302350.
2
The prevalence of common BRCA1 and BRCA2 mutations among Ashkenazi Jews.阿什肯纳兹犹太人中常见的BRCA1和BRCA2基因突变的流行率。
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Modeling the probability that Ashkenazi Jewish women carry a founder mutation in BRCA1 or BRCA2.模拟阿什肯纳兹犹太女性携带BRCA1或BRCA2基因始祖突变的概率。
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Ann N Y Acad Sci. 1997 Dec 29;833:198-203. doi: 10.1111/j.1749-6632.1997.tb48610.x.
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Breast cancer genes--what are the real risks?乳腺癌基因——真正的风险是什么?
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New BRCA2 mutation in an Ashkenazi Jewish family with breast and ovarian cancer.
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Prevalence of BRCA1 and BRCA2 mutations in Korean breast cancer patients.韩国乳腺癌患者中BRCA1和BRCA2基因突变的患病率。
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2
Prevalence of BRCA1 in a hospital-based population of Dutch breast cancer patients.荷兰乳腺癌患者医院人群中BRCA1的患病率。
Br J Cancer. 2000 Sep;83(6):719-24. doi: 10.1054/bjoc.2000.1331.

本文引用的文献

1
The prevalence of common BRCA1 and BRCA2 mutations among Ashkenazi Jews.阿什肯纳兹犹太人中常见的BRCA1和BRCA2基因突变的流行率。
Am J Hum Genet. 1999 Apr;64(4):963-70. doi: 10.1086/302320.
2
Efficacy of bilateral prophylactic mastectomy in women with a family history of breast cancer.双侧预防性乳房切除术对有乳腺癌家族史女性的疗效。
N Engl J Med. 1999 Jan 14;340(2):77-84. doi: 10.1056/NEJM199901143400201.
3
Population-based study of risk of breast cancer in carriers of BRCA2 mutation.基于人群的BRCA2基因突变携带者患乳腺癌风险的研究。
Lancet. 1998 Oct 24;352(9137):1337-9. doi: 10.1016/s0140-6736(98)03300-5.
4
Frequency and carrier risk associated with common BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer patients.阿什肯纳兹犹太乳腺癌患者中常见BRCA1和BRCA2突变的频率及携带者风险。
Am J Hum Genet. 1998 Jul;63(1):45-51. doi: 10.1086/301903.
5
Effect of smoking on breast cancer in carriers of mutant BRCA1 or BRCA2 genes.吸烟对携带BRCA1或BRCA2基因突变者患乳腺癌的影响。
J Natl Cancer Inst. 1998 May 20;90(10):761-6. doi: 10.1093/jnci/90.10.761.
6
Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium.乳腺癌家族中BRCA1和BRCA2基因的遗传异质性及外显率分析。乳腺癌连锁协会。
Am J Hum Genet. 1998 Mar;62(3):676-89. doi: 10.1086/301749.
7
BRCA1 sequence analysis in women at high risk for susceptibility mutations. Risk factor analysis and implications for genetic testing.对具有易感性突变高风险女性的BRCA1基因序列分析。风险因素分析及对基因检测的意义。
JAMA. 1997 Oct 15;278(15):1242-50.
8
Does oral contraceptive use increase the risk of breast cancer in women with BRCA1/BRCA2 mutations more than in other women?与其他女性相比,携带BRCA1/BRCA2基因突变的女性使用口服避孕药会增加患乳腺癌的风险吗?
Cancer Res. 1997 Sep 1;57(17):3678-81.
9
Study of a single BRCA2 mutation with high carrier frequency in a small population.对一个小群体中具有高携带频率的单一BRCA2突变的研究。
Am J Hum Genet. 1997 May;60(5):1079-84.
10
Differential contributions of BRCA1 and BRCA2 to early-onset breast cancer.BRCA1和BRCA2对早发性乳腺癌的不同贡献。
N Engl J Med. 1997 May 15;336(20):1416-21. doi: 10.1056/NEJM199705153362003.