Liberman E A
Biofizika. 1976 Jul-Aug;21(4):639-42.
Methods of coding the number and search for molecular program in a molecular computer are considered. The limited length of the nucleotide code is (see formula) where Pi -- probability of request of the given program, N -- total number of programs. Energetic expenditures for the synthesis of the code with the length l (in an ideal case without noise) E approximately 10 kT X l. Protein-nucleic recognition allows the work of the cell with almost the same expenditures on the account of Brown search in the presence of noise.
考虑了在分子计算机中对分子程序的数量进行编码和搜索的方法。核苷酸编码的有限长度为(见公式),其中Pi——给定程序的请求概率,N——程序总数。在理想情况下无噪声时,合成长度为l的编码的能量消耗E约为10kT×l。在存在噪声的情况下,通过布朗搜索,蛋白质-核酸识别使细胞能够以几乎相同的能量消耗进行工作。