Yamanishi Y, Maeda H, Konishi F, Hiyama K, Yamana S, Ishioka S, Yamakido M
Second Department of Internal Medicine, Hiroshima University School of Medicine, Japan.
Scand J Rheumatol. 1999;28(1):58-61. doi: 10.1080/03009749950155805.
We describe two cases of dermatomyositis (DM), which subsequently developed into rapidly progressive fatal interstitial pneumonitis and pneumomediastinum during steroid therapy. Both cases showed the classical cutaneous manifestations of DM, but the muscular symptoms were absent or mild. Both rapidly progressive interstitial pneumonitis and pneumomediastinum can occur in DM showing less inflammatory changes in the muscles. Patients with this form should be treated with extreme caution.
我们描述了两例皮肌炎（DM）病例，这两例患者在接受类固醇治疗期间随后发展为快速进展性致命性间质性肺炎和气纵隔。两例均表现出皮肌炎的典型皮肤表现，但肌肉症状不存在或轻微。快速进展性间质性肺炎和气纵隔均可发生于肌肉炎症变化较少的皮肌炎患者中。对于这种类型的患者应极其谨慎地进行治疗。
