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[恶性软组织肿瘤的手术及多模式治疗的决定因素]

[Determinants for operative and multimodal treatment of malignant soft tissue tumors].

作者信息

Schlag P M, Hohenberger P

机构信息

Klinik für Chirurgie und Chirurgische Onkologie, Robert-Rössle-Klinik, Universitätsklinikum Charité, Humboldt-Universität zu Berlin.

出版信息

Verh Dtsch Ges Pathol. 1998;82:64-6.

Abstract

An optimal treatment of soft tissue sarcomas is influenced by multiple factors. An improvement of the still unfavourable prognosis for some patients with soft tissue sarcomas with a high local recurrence rate, oftly based on an inadequate surgical primary therapy, can be achieved only if guidelines described in this paper gain increasing influence in practice. The treatment concept for malignant soft tissue sarcomas must be worked out a priori interdisciplinary after knowledge of all relevant dates and findings. Surgery is here only one, but at the right time an essential component of therapy. The R0 resection is an important requirement for a freedom of local recurrence, but the influence of a local recurrence on overall survival remains controversial. Therefore amputations should be taken into consideration only after exhaustion of all available procedures.

摘要

软组织肉瘤的最佳治疗受多种因素影响。对于一些局部复发率高的软组织肉瘤患者,其预后仍然不佳,往往是由于初次手术治疗不充分。只有当本文所述的指南在实践中发挥越来越大的作用时,才能改善这种情况。恶性软组织肉瘤的治疗理念必须在了解所有相关数据和检查结果后,事先进行多学科制定。手术只是其中一个方面,但在合适的时机是治疗的重要组成部分。R0切除是实现局部无复发的重要要求,但局部复发对总生存期的影响仍存在争议。因此,只有在所有可用方法都用尽后才应考虑截肢。

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