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Phenotypic and genotypic investigations of a healthy volunteer deficient in the conversion of losartan to its active metabolite E-3174.

作者信息

McCrea J B, Cribb A, Rushmore T, Osborne B, Gillen L, Lo M W, Waldman S, Bjornsson T, Spielberg S, Goldberg M R

机构信息

Merck Research Laboratories, West Point, Clinical Pharmacology, PA 19486, USA.

出版信息

Clin Pharmacol Ther. 1999 Mar;65(3):348-52. doi: 10.1016/S0009-9236(99)70114-1.

DOI:10.1016/S0009-9236(99)70114-1
PMID:10096267
Abstract
摘要

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Phenotypic and genotypic investigations of a healthy volunteer deficient in the conversion of losartan to its active metabolite E-3174.
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