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[胰高血糖素在急性胰腺炎治疗中的应用(临床贡献)]

[Glucagon in the treatment of acute pancreatitis (clinical contribution)].

作者信息

Polto F, Vadalà G, Platania P, Cirino E

出版信息

Chir Ital. 1976 Apr;28(2):163-70.

PMID:1009641
Abstract

16 patients suffering from acute pancreatitis were treated by intramuscular or intravenous administration of glucagon, with control of the amylasemia and amylasuria values at the start of treatment, the 12th hour and the 36th hour. By the 12th hour from the start of therapy they already observed a reduction in amylasemia and amylasuria to normal values, with disappearance of the symptomatology (pains, vomiting, shock) and complete cure of the patients in 94% of cases. On the basis of their own and others' experience, the Authors therefore believe that glucagon can advantageously be used in this disease, which is characterised by much higher mortality if treated with the traditional therapeutic means.

摘要

16例急性胰腺炎患者接受了胰高血糖素肌肉注射或静脉注射治疗,在治疗开始时、第12小时和第36小时对血淀粉酶和尿淀粉酶值进行了监测。从治疗开始后的第12小时起,他们已观察到血淀粉酶和尿淀粉酶降至正常值,症状(疼痛、呕吐、休克)消失,94%的患者完全治愈。基于他们自己和他人的经验,作者因此认为胰高血糖素可有效地用于这种疾病,而如果采用传统治疗方法,这种疾病的死亡率要高得多。

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