Byzov A L, Maksimov V V
Institute of Information Transmission Problems of the Russian Acad. Sci., Moscow, Russia.
Ross Fiziol Zh Im I M Sechenova. 1998 Oct;84(10):1074-84.
Electrical feedback in chemical synapses and the efficacy of synaptic transmission grow with the increase in the gap resistance, so they should be higher in invaginated synapses than in the flat ones. So the plastic changes in the invagination depth may provide a morphological basis for long-term changes in synaptic efficacy: long-term potentiation (LTP) in brain and retinal synapses. In retinal photoreceptor triad synapses, the electrical feedback can provide an "operational" (instantaneous) control of synaptic transmission.
化学突触中的电反馈以及突触传递的效能会随着间隙电阻的增加而增强,因此在凹陷型突触中它们应比扁平型突触更高。所以凹陷深度的可塑性变化可能为突触效能的长期变化提供形态学基础:大脑和视网膜突触中的长时程增强(LTP)。在视网膜光感受器三联突触中,电反馈可以对突触传递提供“操作性”(即时)控制。