Inoue T, Ohno Y, Takahshi M, Sofuni T, Nakadate M, Korokawa Y
Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho Hokoku. 1998(116):149-52.
From FY 1990, studies aimed at development and improvement of toxicity guidelines have been conducted at the Biological Safety Research Center, in collaboration with the Environmental Health Bureau. To date, researches have focused on acute toxicity, antigenicity, reproductive toxicity, immunotoxicity, etc. In this report, brief summary of studies on cytotoxicity, toxicokinetics, neurotoxicity, genetic toxicity and structure-activity relationship performed during FY 1995-97, is presented.
自1990财年起，生物安全研究中心与环境卫生局合作开展了旨在制定和完善毒性指南的研究。迄今为止，研究主要集中在急性毒性、抗原性、生殖毒性、免疫毒性等方面。本报告简要总结了1995 - 1997财年期间进行的细胞毒性、毒代动力学、神经毒性、遗传毒性及构效关系研究。
