Patel A, Hogan P, Walder B
Department of Dermatology, Sydney Children's Hospital, Randwick, Australia.
Australas J Dermatol. 1999 Feb;40(1):37-40. doi: 10.1046/j.1440-0960.1999.00314.x.
Two immunodeficient children, aged 4 and 12 years, with crusted scabies were successfully treated with a single oral dose of ivermectin (200 micrograms/kg). One child had been diagnosed in infancy with an undefined congenital T cell immunodeficiency and the other with chronic mucocutaneous candidiasis. Both had failed to respond to conventional topical therapy. In view of the excellent therapeutic response and absence of side-effects, ivermectin should be considered in the treatment of recalcitrant crusted scabies in children.
两名患有结痂性疥疮的免疫缺陷儿童，年龄分别为4岁和12岁，单次口服伊维菌素（200微克/千克）后得到成功治疗。一名儿童在婴儿期被诊断患有不明先天性T细胞免疫缺陷，另一名患有慢性黏膜皮肤念珠菌病。两人对传统局部治疗均无反应。鉴于治疗效果极佳且无副作用，在治疗儿童顽固性结痂性疥疮时应考虑使用伊维菌素。
