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CD13——不仅仅是白血病分型中的一个标志物。

CD13--not just a marker in leukemia typing.

作者信息

Riemann D, Kehlen A, Langner J

机构信息

Institute of Medical Immunology, Martin Luther University Halle-Wittenberg, Germany.

出版信息

Immunol Today. 1999 Feb;20(2):83-8. doi: 10.1016/s0167-5699(98)01398-x.

DOI:10.1016/s0167-5699(98)01398-x
PMID:10098327
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7141563/
Abstract

Membrane peptidases are a multifunctional group of ectoenzymes that have been implicated in the control of growth and differentiation of many cellular systems. Here, using aminopeptidase N/CD13 as an example, Dagmar Riemann and colleagues discuss the role of cell-cell contact in peptidase regulation and the influence of peptidases on cellular functions.

摘要

膜肽酶是一类多功能的胞外酶，与许多细胞系统的生长和分化控制有关。在此，以氨肽酶N/CD13为例，达格玛·黎曼及其同事讨论了细胞间接触在肽酶调节中的作用以及肽酶对细胞功能的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dcd/7141563/69535f7e4913/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dcd/7141563/4e17521b33a0/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dcd/7141563/69535f7e4913/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dcd/7141563/4e17521b33a0/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dcd/7141563/69535f7e4913/gr2.jpg

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CD13--not just a marker in leukemia typing.CD13——不仅仅是白血病分型中的一个标志物。
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2
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Enzymatic activity is not a precondition for the intracellular calcium increase mediated by mAbs specific for aminopeptidase N/CD13.酶活性并非由氨肽酶N/CD13特异性单克隆抗体介导的细胞内钙增加的先决条件。
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本文引用的文献

1
Functional comparison of two human monocyte chemotactic protein-2 isoforms, role of the amino-terminal pyroglutamic acid and processing by CD26/dipeptidyl peptidase IV.两种人单核细胞趋化蛋白-2同工型的功能比较、氨基末端焦谷氨酸的作用及CD26/二肽基肽酶IV的加工处理
Biochemistry. 1998 Sep 8;37(36):12672-80. doi: 10.1021/bi980497d.
2
Processing by CD26/dipeptidyl-peptidase IV reduces the chemotactic and anti-HIV-1 activity of stromal-cell-derived factor-1alpha.CD26/二肽基肽酶IV的作用会降低基质细胞衍生因子-1α的趋化性和抗HIV-1活性。
FEBS Lett. 1998 Jul 31;432(1-2):73-6. doi: 10.1016/s0014-5793(98)00830-8.
3
c-Maf interacts with c-Myb to regulate transcription of an early myeloid gene during differentiation.
一种新型的氨肽酶 N/CD13 抑制剂在与蛋白偶联后，可选择性地针对 CD13 的一种内皮形式。
Cell Mol Life Sci. 2024 Jan 30;81(1):68. doi: 10.1007/s00018-023-05102-1.
4
Cancer-specific glycosylation of CD13 impacts its detection and activity in preclinical cancer tissues.CD13的癌症特异性糖基化影响其在临床前癌症组织中的检测及活性。
iScience. 2023 Oct 16;26(11):108219. doi: 10.1016/j.isci.2023.108219. eCollection 2023 Nov 17.
5
Aminopeptidase N/CD13 Crosslinking Promotes the Activation and Membrane Expression of Integrin CD11b/CD18.氨基肽酶 N/CD13 交联促进整合素 CD11b/CD18 的激活和膜表达。
Biomolecules. 2023 Oct 6;13(10):1488. doi: 10.3390/biom13101488.
6
Radiolabeled NGR-Based Heterodimers for Angiogenesis Imaging: A Review of Preclinical Studies.用于血管生成成像的放射性标记基于NGR的异二聚体：临床前研究综述
Cancers (Basel). 2023 Sep 7;15(18):4459. doi: 10.3390/cancers15184459.
7
Crosslinking of membrane CD13 in human neutrophils mediates phagocytosis and production of reactive oxygen species, neutrophil extracellular traps and proinflammatory cytokines.人中性粒细胞膜 CD13 的交联介导吞噬作用和活性氧物质、中性粒细胞胞外诱捕网和促炎细胞因子的产生。
Front Immunol. 2022 Nov 10;13:994496. doi: 10.3389/fimmu.2022.994496. eCollection 2022.
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Tissue Eng Regen Med. 2022 Feb;19(1):73-82. doi: 10.1007/s13770-021-00398-1. Epub 2021 Oct 29.
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Cancer Manag Res. 2021 Jun 4;13:4483-4495. doi: 10.2147/CMAR.S300515. eCollection 2021.
c-Maf与c-Myb相互作用，在分化过程中调节一个早期髓系基因的转录。
Mol Cell Biol. 1998 May;18(5):2729-37. doi: 10.1128/MCB.18.5.2729.
4
The structure and function of CD26 in the T-cell immune response.CD26在T细胞免疫反应中的结构与功能。
Immunol Rev. 1998 Feb;161:55-70. doi: 10.1111/j.1600-065x.1998.tb01571.x.
5
Dipeptidyl-peptidase IV/CD26 on T cells: analysis of an alternative T-cell activation pathway.T细胞上的二肽基肽酶IV/CD26：另一种T细胞激活途径的分析
Immunol Rev. 1998 Feb;161:43-53. doi: 10.1111/j.1600-065x.1998.tb01570.x.
6
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Mol Cell Biol. 1998 Apr;18(4):2218-29. doi: 10.1128/MCB.18.4.2218.
7
Amino-terminal truncation of chemokines by CD26/dipeptidyl-peptidase IV. Conversion of RANTES into a potent inhibitor of monocyte chemotaxis and HIV-1-infection.CD26/二肽基肽酶IV对趋化因子的氨基端截短。RANTES转化为单核细胞趋化和HIV-1感染的强效抑制剂。
J Biol Chem. 1998 Mar 27;273(13):7222-7. doi: 10.1074/jbc.273.13.7222.
8
Characterization of Glu350 as a critical residue involved in the N-terminal amine binding site of aminopeptidase N (EC 3.4.11.2): insights into its mechanism of action.
Biochemistry. 1998 Jan 13;37(2):686-92. doi: 10.1021/bi971705p.
9
Regulation of the receptor specificity and function of the chemokine RANTES (regulated on activation, normal T cell expressed and secreted) by dipeptidyl peptidase IV (CD26)-mediated cleavage.二肽基肽酶IV（CD26）介导的裂解对趋化因子RANTES（活化调节、正常T细胞表达和分泌）受体特异性和功能的调控
J Exp Med. 1997 Dec 1;186(11):1865-72. doi: 10.1084/jem.186.11.1865.
10
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J Leukoc Biol. 1997 Nov;62(5):612-9. doi: 10.1002/jlb.62.5.612.