van der Linde-Sipman J S, van den Ingh T S, van nes J J, Verhagen H, Kersten J G, Beynen A C, Plekkringa R
Department of Pathology, Faculty of Veterinary Medicine, Utrecht University, The Netherlands.
Vet Pathol. 1999 Mar;36(2):152-6. doi: 10.1354/vp.36-2-152.
In April 1996, an outbreak of toxic polyneuropathy in cats occurred in the Netherlands. All cats had been fed one of two brands of dry cat food from one manufacturer. Chemical analyses of these foods, stomach contents, and liver and kidney of affected cats revealed contamination with the ionophor salinomycin. Epidemiologic and clinical data were collected from 823 cats, or about 1% of the cats at risk. In 21 affected cats, postmortem examination was performed. The affected cats had acute onset of lameness and paralysis of the hindlimbs followed by the forelimbs. Clinical and pathologic examination indicated a distal polyneuropathy involving both the sensory and motor nerves.
1996年4月，荷兰发生了一起猫中毒性多发性神经病疫情。所有猫都食用了同一家制造商生产的两种品牌干猫粮中的一种。对这些猫粮、胃内容物以及患病猫的肝脏和肾脏进行化学分析后发现，它们被离子载体盐霉素污染。从823只猫（约占风险猫数量的1%）收集了流行病学和临床数据。对21只患病猫进行了尸检。患病猫急性发病，后肢继而前肢出现跛行和瘫痪。临床和病理检查表明，这是一种涉及感觉神经和运动神经的远端多发性神经病。
