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精神分裂症中的神经认知与社会功能

Neurocognitive and social functioning in schizophrenia.

作者信息

Addington J, Addington D

机构信息

Department of Psychiatry, University of Calgary, Alberta, Canada.

出版信息

Schizophr Bull. 1999;25(1):173-82. doi: 10.1093/oxfordjournals.schbul.a033363.

Abstract

This cross-sectional study examined the relationships between neurocognitive and social functioning in a sample of 80 outpatients with DSM-III-R schizophrenia. The neurocognitive battery included measures of verbal ability, verbal memory, visual memory, executive functioning, visual-spatial organization, vigilance, and early information processing. Positive and negative symptoms were assessed with the Positive and Negative Syndrome Scale. A range of social behaviors were assessed using the Social Functioning Scale (SFS), the Quality of Life Scale (QLS), and a video-based test, the Assessment of Interpersonal Problem-Solving Skills (AIPSS). Social functioning as assessed by the SFS was unrelated to neurocognitive functioning. Poor cognitive flexibility was associated with low scores on the QLS and the AIPSS. Verbal ability and verbal memory were also significantly associated with the AIPSS. Visual-spatial ability and vigilance were associated with the sending skills subscale of the AIPSS. In this study, which used a wide range of neurocognitive tests and measures of community functioning and social problem solving, results support earlier research that suggests an association between certain aspects of neurocognitive functioning and social functioning.

摘要

这项横断面研究考察了80名符合《精神疾病诊断与统计手册第三版修订本》(DSM-III-R)的精神分裂症门诊患者样本中神经认知功能与社会功能之间的关系。神经认知测试组包括言语能力、言语记忆、视觉记忆、执行功能、视觉空间组织、警觉性和早期信息处理等方面的测量。使用阳性和阴性症状量表评估阳性和阴性症状。采用社会功能量表(SFS)、生活质量量表(QLS)以及基于视频的人际问题解决技能评估(AIPSS)对一系列社会行为进行评估。SFS评估的社会功能与神经认知功能无关。认知灵活性差与QLS和AIPSS得分低相关。言语能力和言语记忆也与AIPSS显著相关。视觉空间能力和警觉性与AIPSS的发送技能子量表相关。在这项使用了广泛的神经认知测试以及社区功能和社会问题解决测量方法的研究中,结果支持了早期研究,即表明神经认知功能的某些方面与社会功能之间存在关联。

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