Moussa M A, Shaltout A A, Nkansa-Dwamena D, Mourad M, Alsheikh N, Agha N, Galal D O
Department of Community Medicine & Behavioural Sciences, Faculty of Medicine, Kuwait University, Safat.
Eur J Epidemiol. 1999 Jan;15(1):41-9. doi: 10.1023/a:1007556608104.
The prevalence of adult obesity in Kuwait is among the highest in the Arab peninsula, and cardiovascular disease, for which obesity is a risk factor, is the leading cause of death. This study reports familial and environmental factors associated with childhood obesity; in addition to adverse effects of obesity on children's serum lipids, lipoproteins, apolipoproteins, insulin, and blood pressure profiles. The authors carried out a pair-matched case-control study including 460 obese (body mass index >90th percentile of the age/sex specific reference value of the National Center for Health Statistics), school children 6 to 13 years old matched by age and gender to 460 normal weight controls. We ascertained obese children in a cross-sectional survey of a representative sample of 2400 school children selected from 20 schools by multistage stratified random sampling. Biochemical variables and blood pressure were adversely affected in obese children. The conditional logistic regression analysis showed that family history of obesity, and diabetes mellitus, respiratory and bone diseases in child were significant associated factors with obesity after adjusting for social and behavioural factors. Physical activity and parental social class were not significant. We recommend early preventive measures with emphasis on families in which one or both parents are overweight.
科威特成人肥胖率在阿拉伯半岛位居前列,而肥胖作为风险因素的心血管疾病是主要死因。本研究报告了与儿童肥胖相关的家庭和环境因素;此外,还报告了肥胖对儿童血清脂质、脂蛋白、载脂蛋白、胰岛素和血压状况的不良影响。作者开展了一项配对病例对照研究,纳入了460名肥胖(体重指数>美国国家卫生统计中心年龄/性别特异性参考值的第90百分位数)的6至13岁学龄儿童,按年龄和性别与460名正常体重对照进行匹配。我们通过多阶段分层随机抽样从20所学校选取2400名学童的代表性样本进行横断面调查,确定肥胖儿童。肥胖儿童的生化指标和血压受到不利影响。条件逻辑回归分析显示,在调整社会和行为因素后,肥胖家族史以及儿童的糖尿病、呼吸系统疾病和骨骼疾病是与肥胖显著相关的因素。身体活动和父母社会阶层不显著。我们建议采取早期预防措施,重点关注父母一方或双方超重的家庭。