Vakil N
University of Wsiconsin Medical School, Milwaukee, WI 53233, USA.
Am J Ther. 1998 May;5(3):197-201. doi: 10.1097/00045391-199805000-00011.
Helicobacter pylori infection has been shown to be the principal cause of peptic ulcer disease and has been associated with MALT lymphoma and gastric cancer. Eradication of H. pylori has been shown to change the natural history of peptic ulcer disease by preventing relapse and to reduce health care expenditures when compared with traditional therapy. Two-drug regimens have been superceded by three-drug regimens because they are more effective in eradication. Therapies with the highest efficacy are cost-effective because failed eradication is associated with high costs.
幽门螺杆菌感染已被证明是消化性溃疡疾病的主要病因，并且与黏膜相关淋巴组织淋巴瘤和胃癌有关。与传统疗法相比，根除幽门螺杆菌已被证明可通过预防复发改变消化性溃疡疾病的自然病程，并降低医疗保健支出。两药方案已被三药方案取代，因为三药方案在根除方面更有效。疗效最高的疗法具有成本效益，因为根除失败会带来高昂成本。
