抗病毒核苷、阿昔洛韦和齐多夫定的5'-氨基酸酯可通过肠道PEPT1肽转运体吸收。 - Suppr | 超能文献

"5'-Amino acid esters of antiviral nucleosides, acyclovir, and AZT are absorbed by the intestinal PEPT1 peptide transporter,".

作者信息

Amidon G L, Walgreen C R

出版信息

Pharm Res. 1999 Feb;16(2):175. doi: 10.1023/a:1011955803803.

DOI:10.1023/a:1011955803803

Abstract

摘要

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Pharm Res. 1999 Feb;16(2):175. doi: 10.1023/a:1011955803803.

2

5'-Amino acid esters of antiviral nucleosides, acyclovir, and AZT are absorbed by the intestinal PEPT1 peptide transporter.抗病毒核苷、阿昔洛韦和齐多夫定的5'-氨基酸酯可通过肠道PEPT1肽转运体吸收。

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3

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Cellular uptake mechanism of amino acid ester prodrugs in Caco-2/hPEPT1 cells overexpressing a human peptide transporter.在过表达人肽转运体的Caco-2/hPEPT1细胞中氨基酸酯前药的细胞摄取机制

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Valacyclovir: a substrate for the intestinal and renal peptide transporters PEPT1 and PEPT2.伐昔洛韦：肠道和肾脏肽转运体PEPT1和PEPT2的底物。

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Rat multispecific organic anion transporter 1 (rOAT1) transports zidovudine, acyclovir, and other antiviral nucleoside analogs.大鼠多特异性有机阴离子转运体1（rOAT1）可转运齐多夫定、阿昔洛韦及其他抗病毒核苷类似物。

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Interactions of a nonpeptidic drug, valacyclovir, with the human intestinal peptide transporter (hPEPT1) expressed in a mammalian cell line.一种非肽类药物伐昔洛韦与在哺乳动物细胞系中表达的人肠道肽转运体（hPEPT1）的相互作用。

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