[Research on nitrogen heterocyclic compounds. X. New method of synthesis of pyrrolo/1,2-a/quinoline and its derivatives].

The synthesis of pyrrolo[1,2-a]quinoline derivatives from 1-arylpyrroles bearing an acetic acid or acetonitrile moiety on the benzene or pyrrole nucleus is described. Pyrrolo [1,2-a]quinoline derivatives have some pharmaceutical interest as cyclic analogues of 9H-pyrrolo[1,2-a]indole and 5H-pyrrolo[2,1-c] [1,4]-benzodiazepine, the basic structures of the antitumor antibiotics mitomycin C, anthramycin and tomaymycin.