Bedrov Ia A, Shekhter S Iu, Shcherba M M
Fiziol Zh SSSR Im I M Sechenova. 1976 Sep;62(9):1343-8.
In mouse with posttransfusion polycytemia, depression of erythropoiesis suggests that, in response to erythrocytes transfusion, not only the differentiation of erythropoietin-sensitive cells is interrupted (cessation of inflow of the labelled erythrocytes into the circulation on the 8th day), but the proligeration of differentiated erythroid precursors is also inhibited (fall of amount of labelled erythrocytes during first days). This was corroborated by analysis of the experimental data with the aid of mathematical model of erythropoiesis. The model revealed that, in posttransfusion polycytemia, division of 40 percent of all divisionable erythroid precursors was halted.
在输血后红细胞增多症的小鼠中，红细胞生成受抑制表明，对红细胞输血的反应中，不仅促红细胞生成素敏感细胞的分化被中断（第8天标记红细胞进入循环停止），而且已分化的红系前体细胞的增殖也受到抑制（最初几天标记红细胞数量下降）。借助红细胞生成的数学模型对实验数据的分析证实了这一点。该模型显示，在输血后红细胞增多症中，所有可分裂的红系前体细胞中有40%的分裂被停止。
