Petelenz T, Kozakiewicz K, Nowak S, Flak Z, Czyz Z
III Kliniki Kardiologii, Slaskiej Akademii Medycznej w Katowicach.
Pol Merkur Lekarski. 1998 Sep;5(27):117-9.
One of the coronary disease diagnostic methods of big sensitivity and specificity is perfusive effort scintrigraphy of myocardium by means of thallium-201. For few years the dipyridamole test has been applied instead of the effort test. Perfusive scintigraphy of myocardium after provocative treatment by means of dipyridamole and then selective coronary arteriography of coronary vessels, have been carried out at 25 patients with ischemia. These studies showed almost 100% of conformability with exposing the ischemia zones in scintigraphy and coronary arteriography in cases of coronary vessels contraction over 50%. The dipyridamole test also revealed the ischemzones in myocardium that are in agreement with coronary vascularization deficiency. That test can be utilized in revealing the coronary disease and is helpful in qualifying patients for coronary arteriography. At the same time studies that have been carried out prove that applying dipyridamole is absolutely contraindicated in treating of coronary disease of the organic background.
一种具有高灵敏度和特异性的冠心病诊断方法是利用铊 - 201进行心肌灌注负荷闪烁扫描。近年来，双嘧达莫试验已被用于替代负荷试验。对25例缺血患者进行了双嘧达莫激发治疗后的心肌灌注闪烁扫描，然后对冠状动脉进行选择性冠状动脉造影。这些研究表明，在冠状动脉收缩超过50%的情况下，闪烁扫描和冠状动脉造影中显示的缺血区域几乎100%相符。双嘧达莫试验还揭示了与冠状动脉血管化不足相符的心肌缺血区域。该试验可用于揭示冠心病，并有助于确定患者是否适合进行冠状动脉造影。同时，已开展的研究证明，在器质性背景的冠心病治疗中，绝对禁止使用双嘧达莫。
