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[临床病史在肾血管性高血压初步诊断中的意义]

[Significance of clinical anamnesis in the preliminary diagnosis of renovascular hypertension].

作者信息

Smoszna J, Wańkowicz Z

机构信息

Kliniki Nefrologii ze Stacja Dializ Centralnego Szpitala Klinicznego Wojskowej Akademii Medycznej, Warszawie.

出版信息

Pol Merkur Lekarski. 1998 Nov;5(29):266-8.

Abstract

Differences in the occurrence of renovascular hypertension (RVH) in the population of patients with arterial hypertension related to different preselection criteria induced us to analyse practical usefulness of clinical anamnesis for RVH. In 130 patients with arterial hypertension (72 women, 58 men, average age 48 years) and clinical suspicion on RVH, the initial renal angioscintigraphy (with 99m Tc-DTPA) was abnormal, demonstrating impairment of glomerular filtration rate. In the whole group captopril angioscintigraphy test (CAT) as well as captopril renin test (CRT) were simultaneously performed according to own protocol. In 24 cases highly suspected for RVH on the ground of clinical anamnesis the critical stenosis of renal artery (> 75% of the lumen) was found in the arteriography. The most significant signs of RVH in clinical anamnesis were the following: the diastolic blood pressure > 120 mm Hg (92% cases), resistance to 3 hypertensive drugs (92%), sudden onset and rapidly progressive course of hypertension (88%) and advanced hypertension retinopathy (79%). On the ground of these results, detailed clinical anamnesis is recommended as a cheap and easy preselection test for RVH in the hypertensive population.

摘要

在患有动脉高血压的患者群体中,因不同的预筛选标准导致肾血管性高血压(RVH)发生率存在差异,这促使我们分析临床病史对RVH的实际应用价值。对130例患有动脉高血压(72例女性,58例男性,平均年龄48岁)且临床怀疑患有RVH的患者进行了初步肾血管闪烁造影(使用99m锝 - 二乙三胺五乙酸),结果显示肾小球滤过率受损。在整个研究组中,根据我们自己的方案同时进行了卡托普利血管闪烁造影试验(CAT)以及卡托普利肾素试验(CRT)。在24例基于临床病史高度怀疑患有RVH的病例中,血管造影发现肾动脉临界狭窄(管腔狭窄> 75%)。临床病史中RVH最显著的体征如下:舒张压> 120 mmHg(92%的病例)、对3种降压药物耐药(92%)、高血压突然发作且病程进展迅速(88%)以及严重高血压视网膜病变(79%)。基于这些结果,建议详细的临床病史作为高血压人群中RVH的一种廉价且简便的预筛选检查。

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